Robust Method in Calculation of Reference Interval

This robust method is used to calculate the reference interval on small sample size (below to 120 observations).

Usage

robustRI(x, ind = 1:length(x), conf.level = 0.95, tol = 1e-06)

Arguments

x

(numeric)
numeric measurements from target population.

ind

(integer)
integer vector for boot process, default is all elements in x.

conf.level

(numeric)
significance level for the internal t statistic.

tol

(numeric)
tolerance for when the iterative process can be stopped.

Value

a vector of robust reference interval

References

This robust algorithm is referring to CLSI document EP28A3.

Examples

# This example data is taken from EP28A3 Appendix B. to ensure the result is in accordance.
x <- c(8.9, 9.2, rep(9.4, 2), rep(9.5, 3), rep(9.6, 4), rep(9.7, 5), 9.8, rep(9.9, 2), 10.2)
robustRI(x)
#> [1]  9.049545 10.199396